수종 Flavonoids 의 우식원인균에 대한 항세균효과
Antibacterial Effect of Some Flavonoids against Cariogenic Bacteria
정대인, 노재승, 장기완,
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정대인 ( Chung Dae-In ) - 전북대학교 치과대학 예방치학교실
노재승 ( Ro Jae-Seung ) - 전북대학교 치과대학 예방치학교실
장기완 ( Chang Kee-Wan ) - 전북대학교 치과대학 예방치학교실
KMID : 0355419960200020189
Abstract
Flavonoids are phenolic compounds synthesized by vascular plants, fruits, and vegetables which have varied effects on mammalian cell systems. This study was designed to investigate the effects of some flavonoids on the growth against
Streptococcus mutans KCTC 3065, Lactobacillus acidophilus KCTC 3111, and Actinomyces Naeslundii KCTC 9013 in vitro. Minimal concentration and zone of inhibition the agar plate were measured to investigate the antimicrobial effects of the flavonoids against the strains. In the S. mutans strain, naringenin and phloretin inhibited the growth most effectively when the strain was cultured for 48 hours at 37°C anaerobically, and the minimal inhibitory concentrations of both agents were 0.5 mg per ml. In the L. acidophilus and A. naeslundii strains, phloretin inhibited the growth of these strains under same conditions, and the minimal inhibitory concentrations of the agent was 0.25 mg per ml.
키워드
항세균효과
Flavonoids;Streptococcus mutans;Lactobacilli;Actinomyces
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